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CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (N-Term) Peptide

CTCFL Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN975412

Aperçu rapide pour CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (N-Term) Peptide (ABIN975412)

Antigène

CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))

Origine

Humain

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-CTCFL antibody (Catalog #: ARP36128_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))

    Sujet

    CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. CTCFL is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and CTCFL are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation.CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: BORIS, CTCF-T, MGC163358, dJ579F20.2, CT27, HMGB1L1

    Protein Interaction Partner: BRCA1

    Protein Size: 663

    Poids moléculaire

    76 kDa

    ID gène

    140690

    NCBI Accession

    NM_080618, NP_542185

    UniProt

    Q8NI51
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